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What is iovera Cryoneurolysis?

Cryoneurolysis, also known as the iovera° system, is a state-of-the-art, non-opioid pain management solution that utilizes the power of cold therapy to block pain signals from reaching the brain. This innovative technology targets the sensory nerves responsible for transmitting pain signals from the knee, effectively numbing the treated area and providing significant pain relief.

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Getting Total Knee Replacement? Worried About Post-op Pain?

At our practice, we're dedicated to offering innovative solutions to enhance your comfort and recovery, including when it comes to preparing for total knee replacement surgery. One such cutting-edge treatment we offer is Iovera cryoneurolysis, a revolutionary approach to decreasing postoperative knee pain.

Decreasing Postoperative Knee Pain Prior to Total Knee Replacement

Pain management is crucial for ensuring a smooth and successful recovery following total knee replacement surgery. By undergoing Iovera cryoneurolysis prior to your procedure, you can significantly reduce postoperative pain and discomfort, potentially leading to a faster and more comfortable recovery.


This innovative treatment allows you to approach your surgery with greater confidence and peace of mind, knowing that steps have been taken to minimize your pain and optimize your outcomes.

How Does iovera Cryoneurolysis Work?

During Iovera cryoneurolysis, a small, handheld device is used to deliver controlled cold therapy to specific nerves around the knee joint. The extreme cold temporarily interrupts the nerve signals, effectively "freezing" the nerves and preventing them from transmitting pain sensations. 

Benefits of iovera Cryoneurolysis:

  • Non-opioid pain management solution

  • Targeted pain relief without systemic side effects

  • Improved postoperative comfort and potentially faster recovery

  • Pain relief is immediate and can last 90 days

Who Can Benefit From iovera° Treatment?


People who have osteoarthritis (OA) pain in the knee.


People who are considering knee replacement surgery (iovera° can be done before surgery).


People who are not candidates for surgery or have been avoiding surgery, but need pain relief.

  • How Do I Know If I’m a Candidate for Intracept®?
    The Intracept® Procedure is indicated for patients who have had: Chronic low back pain for at least six months, Who have tried conservative care for at least six months and whose MRI shows features consistent with Modic changes – indicating damage at the vertebral endplates has led to inflammation. The Intracept Procedure, as with any procedure, has risks that should be discussed between the patient and medical provider.
  • How Long Does Pain Relief Last following the Intracept® Procedure?
    Most people start to feel pain relief within 2 weeks after the procedure. Clinical evidence demonstrates the majority of patients experience significant improvements in function and pain 3-months post procedure that are sustained more than 5 years after a single treatment.
  • Is the Intracept® Procedure painful?
    Some patients experience 2-3 days of soreness after the procedure, but overall it is very well tolerated and most patients return to normal activities 24 hours later.
  • What should I expect after the procedure?
    Most patients report at least 50% improvement of their chronic, vertebrogenic low back pain at 2 weeks after the procedure.

Get Relief From Trusted Experts.

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